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Course Description

The mentored K Series is often an applicant’s first contact with the NIH grant process. It can be a steep and intimidating learning curve. We will help you think carefully about whether the K is right for you, as its pursuit may use much of your ESI time. We will discuss how to prepare for and write each section, offering examples from recently funded grant submissions. This writing course may be of particular interest to medical centers seeking to create a robust physician-scientist training pipeline.

Unsure of R vs. K? We suggest that you purchase Master the K (and F) Series writing course, as the Research Strategy portion is identical to Master the R Series.

F applicants: Master the K (and F) Series will help you write a persuasive F-series submission, given the overlap between the two mechanisms. It will also help you hone NIH grantsmanship skills that will improve your applications for years to come.

If you have questions about your specific application or circumstances, please come to one of our live sessions (bi-weekly live Q & A, First Fridays office hours, and Bootcamps) to discuss with Dr. Bouvier. These 1:1 live opportunities are included in your Membership. 

Chapters 1-4 Updated: July 22, 2025

Chapters 5-8 Updated: January 5, 2026

Preview an Excerpt of This Course

Course Details

Who: For those preparing to write an NIH mentored K-series submission (i.e., Career Development Award), and the people who advise them.

When:  Available on demand

Cost: $1500

Summary of Course Sections

1. Preparation

Great science is necessary, but not sufficient, to funding success. Here, I discuss preparatory strategies that distinguish my applicants who are consistently more successful at NIH. Actionable tips include familiarizing yourself with NIH’s funding priorities and finding your niche in the funding portfolio via the RePORTER website. Emphasis is place on navigating the myriad recent changes at NIH. An interactive checklist helps you track your progress through these important steps. 

2. Specific Aims

The one-page Aims document is arguably the most important narrative section of an Ao NIH submission. Packed with templates and samples from recently successful applications, learners will be walked through the writing of an effective narrative overview, a well-constructed "we propose" paragraph, concise aims, and punch impact statements. We then discuss how to use the draft aims page to vet your project idea with the Program Officer and colleagues. The course supplements contain tips, numberous samples from recent successful applications, and a writing exercise that consiste of a funded Aims page into which I have inserted mistakes I typically see. An interactive checklist helps you track your progress. 

3. Significance and Innovation

Applicants often struggle to write the Significance and Innovation sections and to understand the new scoring criteria. I walk learners through the writing of a strong Significance section, which includes the background/rationale, disease burden, the Rigor of Prior Research, and how your project will address the strengths and weaknesses of the prior research and reduce disease burden. I will demonstrate how the Innovation section must drive home the competitive advantage over previous and current approaches. Because reviewers tend to skim text at the review meeting, I emphasize formatting strategies that ensure reviewers won't miss key concepts. Course supplements offer loads of actionable tips, templates, and recently funded samples, and exercises to help you edit and write more competitively. An at-a-glance table and interactive checklist assist in developing a strong draft. 

4. Approach

The Approach section is perhaps the most intuitive yet daunting of the sections to tackle. And now, applicants worry about addressing the new scoring criteria introduced in FORMS-I. I will offer strategies for developing an effective outline and formatting techniques. One by one, we will review templates and samples for each of the sections typically included in the all-important Approach section. Given the changes in the scoring criteria, emphasis will be placed on concrete ways to write effectively about rigor, including many examples from recently funded applications. An interactive checklist will help you write a competitive draft.

5. Overview of the K Series

Should you apply for a K, and if so, which one? To which institute? Are the training plan and mentoring team sound? Does your project fit the training plan? We begin with an overview of the Career Development Awards, the available funding mechanisms, how to choose support by career stage and eligibility, and how to structure your thinking about training topics, mentors, and your project. 

6. Candidate Section

We examine step-by-step how to write each of the 3 parts of the Candidate Section. This course is packed with an array of templates and funded samples from across a wide range of K mechanisms. 

7. Letters

I will discuss how to draft the Letters from mentors, co-mentors, collaborators, contributors, and consultants — which unbeknownst to most K applicants are written in large part by the applicant. We review reference letters and how all these letters differ from one another. We also examine the contents of a winning institutional letter. 

8. Mistakes Commonly Made

I present mistakes I typically see on K submissions based on my assessment of recent Summary Statements from my K applicants.

Course Learning Objectives

At the end of 5 hours 12 minutes of coursework, you will: 

  1. Identify and employ crucial steps to take to prepare to write an NIH grant application
  2. Acquire key information about effective NIH writing strategies
  3. Apply NIH effective strategies to writing and revising a draft submission
  4. Utilize learned skills to critique peer drafts to hone their own skills
  5. Develop better grantwriting skills that will carry forward on all submissions, whether to NIH or other funding agencies


Content Disclaimer

Course content updated January 5, 2026. Content of this course was updated and re-recorded on this date. To our knowledge, the content was accurate at that time. We recommend that you search for changes that may have occurred to the content since the recording date.

Note that the course title may have been modified slightly since the recording.

What our clients say

I didn't know what I didn't know, and am so glad to have come across this training. It has opened a new door in terms of considering different types of grants and provided a framework of communication through grant writing in order to be able to access necessary resources for some of the projects that I am considering in the space of preventive medicine, public health, and primary care. This training was extremely thorough and is an excellent resource to anyone considering applying for K, F, and R series grants, but to anyone who is embarking on a journey to design and fund a project. Being able to go through the process outlined around grant writing is extremely useful for the implementation of a project as well.


Pratiksha Yalakkishettar MD, Family Medicine Physician & Preventive Medicine Fellow, Chan Medical School, University of Massachusetts

Helping over 3000+ learners from all skill levels

Our students have grown their skills by taking our courses. Here are just a few of their stories.

It is very informational and sets a good foundation for my grant writing. I wish I had attended earlier than now and could have gone very far with my grant application.


Eyitayo O. Owolabi PhD, RN
Presidential Postdoctoral Fellow
R1 Research Institution

I completed your K-series course last spring and wrote/submitted my first MOSAIC K99/R00 application in the third cycle. I was beyond thrilled when I received my notice of award and ultimately was awarded an NIGMS MOSAIC K99/R00. Thank you for providing this wonderful resource — it really helped me prepare for writing a competitive K99 grant application. Thank you for all you do in instructing researchers on successful grantsmanship as well as keeping us informed with the latest NIH landscape. I have benefitted greatly from taking your K training.


Iris Smith PhD, Instructor, Department of Molecular Medicine
Top 20 World's Best Hospital

Very, very helpful. In particular, the specific, detailed, and actionable recommendations regarding elements and language to include in the grant is invaluable.


Katharine Collier MD
Medical Oncology Fellow
Top 5 Largest Cancer Hospital

Excellent training. As someone not familiar with the K mechanism, this really helped me understand what goes into K specific materials, like the career development plan. The emphasis and explanation of rigor criteria was also helpful in understanding how to address these in the application. The example materials provided throughout were incredibly useful and clarifying.


Kellie Gross PhD
Faculty Research Training and Development Specialist
Top 5 Largest Cancer Hospital